Aluminum Acetate. Soothing, effective relief of minor skin irritations due to: Poison ivy; Athlete's foot; Insect bites; Rashes. Domeboro provides soothing, effective relief of minor skin irritations. For over 50 years doctors have been recommending Domeboro Astringent Solution to help relieve minor skin irritations. Each powder packet, when mixed in water and ready for use, provides the active ingredient Aluminum Acetate resulting from the reaction of Calcium Acetate 839 mg and Aluminum Sulfate 1191 mg. Made in the U.S.A.